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TitleStructural Basis of Tirasemtiv Activation of Fast Skeletal Muscle.
Journal, issue, pagesJ. Med. Chem., Vol. 64, Page 3026-3034, Year 2021
Publish dateSep 30, 2020 (structure data deposition date)
AuthorsLi, M.X. / Mercier, P. / Hartman, J.J. / Sykes, B.D.
External linksJ. Med. Chem. / PubMed:33703886
MethodsNMR (solution)
Structure data

PDB-7kaa:
NMR solution structures of tirasemtiv drug bound to a fast skeletal troponin C-troponin I complex
Method: SOLUTION NMR

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-W97:
6-ethynyl-1-(pentan-3-yl)-1H-imidazo[4,5-b]pyrazin-2-ol

Source
  • homo sapiens (human)
KeywordsCONTRACTILE PROTEIN / Activator

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