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TitleA vulnerable, membrane-proximal site in human respiratory syncytial virus F revealed by a prefusion-specific single-domain antibody.
Journal, issue, pagesJ. Virol., Vol. 95, Year 2021
Publish dateFeb 26, 2021 (structure data deposition date)
AuthorsRossey, I. / Hsieh, C.L. / Sedeyn, K. / Ballegeer, M. / Schepens, B. / Mclellan, J.S. / Saelens, X.
External linksJ. Virol. / PubMed:33692208
MethodsX-ray diffraction
Resolution1.94 - 2.1 Å
Structure data

PDB-7lvu:
Structure of RSV F-directed VHH Cl184
Method: X-RAY DIFFRACTION / Resolution: 1.94 Å

PDB-7lvw:
Structure of RSV F in Complex with VHH Cl184
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-CL:
Unknown entry

Source
  • lama glama (llama)
  • respiratory syncytial virus
KeywordsIMMUNE SYSTEM / nanobody / VHH / antibody / IMMUNE SYSTEM/VIRAL PROTEIN / fusion protein / virus complex / IMMUNE SYSTEM-VIRAL PROTEIN complex

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