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Structure paper

TitleThe mosquito protein AEG12 displays both cytolytic and antiviral properties via a common lipid transfer mechanism.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 118, Year 2021
Publish dateJul 14, 2020 (structure data deposition date)
AuthorsFoo, A.C.Y. / Thompson, P.M. / Chen, S.H. / Jadi, R. / Lupo, B. / DeRose, E.F. / Arora, S. / Placentra, V.C. / Premkumar, L. / Perera, L. ...Foo, A.C.Y. / Thompson, P.M. / Chen, S.H. / Jadi, R. / Lupo, B. / DeRose, E.F. / Arora, S. / Placentra, V.C. / Premkumar, L. / Perera, L. / Pedersen, L.C. / Martin, N. / Mueller, G.A.
External linksProc. Natl. Acad. Sci. USA / PubMed:33688047
MethodsX-ray diffraction
Resolution1.95 Å
Structure data

PDB-6xrx:
Crystal structure of the mosquito protein AZ1 as an MBP fusion
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
  • aedes aegypti (yellow fever mosquito)
KeywordsLIPID BINDING PROTEIN / mosquito / fatty acids / lipids / anti-viral

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