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TitleStructures of mouse and human GITR-GITRL complexes reveal unique TNF superfamily interactions.
Journal, issue, pagesNat Commun, Vol. 12, Page 1378-1378, Year 2021
Publish dateOct 21, 2020 (structure data deposition date)
AuthorsWang, F. / Chau, B. / West, S.M. / Kimberlin, C.R. / Cao, F. / Schwarz, F. / Aguilar, B. / Han, M. / Morishige, W. / Bee, C. ...Wang, F. / Chau, B. / West, S.M. / Kimberlin, C.R. / Cao, F. / Schwarz, F. / Aguilar, B. / Han, M. / Morishige, W. / Bee, C. / Dollinger, G. / Rajpal, A. / Strop, P.
External linksNat Commun / PubMed:33654081
MethodsX-ray diffraction
Resolution2.95610193196 - 3.20569845167 Å
Structure data

PDB-7khd:
Human GITR-GITRL complex
Method: X-RAY DIFFRACTION / Resolution: 2.95610193196 Å

PDB-7khx:
Mouse GITR-GITRL complex
Method: X-RAY DIFFRACTION / Resolution: 3.20569845167 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / TNFRSF / receptor-ligand complex

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