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Structure paper

TitleThe CRISPR ancillary effector Can2 is a dual-specificity nuclease potentiating type III CRISPR defence.
Journal, issue, pagesNucleic Acids Res., Vol. 49, Page 2777-2789, Year 2021
Publish dateDec 22, 2020 (structure data deposition date)
AuthorsZhu, W. / McQuarrie, S. / Gruschow, S. / McMahon, S.A. / Graham, S. / Gloster, T.M. / White, M.F.
External linksNucleic Acids Res. / PubMed:33590098
MethodsX-ray diffraction
Resolution2.02 Å
Structure data

PDB-7bdv:
Structure of Can2 from Sulfobacillus thermosulfidooxidans in complex with cyclic tetra-adenylate (cA4)
Method: X-RAY DIFFRACTION / Resolution: 2.02 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • sulfobacillus thermosulfidooxidans (bacteria)
  • synthetic construct (others)
KeywordsDNA BINDING PROTEIN / CRISPR / cyclic tetra-adenylate / CARF domains / nuclease

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