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Structure paper

TitleMolecular principles of Piwi-mediated cotranscriptional silencing through the dimeric SFiNX complex.
Journal, issue, pagesGenes Dev., Vol. 35, Page 392-409, Year 2021
Publish dateSep 11, 2020 (structure data deposition date)
AuthorsSchnabl, J. / Wang, J. / Hohmann, U. / Gehre, M. / Batki, J. / Andreev, V.I. / Purkhauser, K. / Fasching, N. / Duchek, P. / Novatchkova, M. ...Schnabl, J. / Wang, J. / Hohmann, U. / Gehre, M. / Batki, J. / Andreev, V.I. / Purkhauser, K. / Fasching, N. / Duchek, P. / Novatchkova, M. / Mechtler, K. / Plaschka, C. / Patel, D.J. / Brennecke, J.
External linksGenes Dev. / PubMed:33574069
MethodsX-ray diffraction
Resolution1.415 - 2.5 Å
Structure data

PDB-7k3j:
Crystal structure of dLC8 in complex with Panoramix TQT+TQ peptide
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-7k3k:
Crystal structure of dLC8 in complex with Panoramix TQT peptide
Method: X-RAY DIFFRACTION / Resolution: 1.415 Å

PDB-7k3l:
Crystal structure of dLC8 in complex with Panoramix TQ peptide
Method: X-RAY DIFFRACTION / Resolution: 1.79 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-EDO:
1,2-ETHANEDIOL

Source
  • drosophila melanogaster (fruit fly)
KeywordsMOTOR PROTEIN / Piwi / transposon silencing / heterochromatin formation / piRNA pathway / transcriptional silencing / RNA BINDING PROTEIN / transposon siliencing

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