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TitleBiophysical and Structural Characterization of Novel RAS-Binding Domains (RBDs) of PI3K alpha and PI3K gamma.
Journal, issue, pagesJ. Mol. Biol., Vol. 433, Page 166838-166838, Year 2021
Publish dateJan 30, 2020 (structure data deposition date)
AuthorsMartinez, N.G. / Thieker, D.F. / Carey, L.M. / Rasquinha, J.A. / Kistler, S.K. / Kuhlman, B.A. / Campbell, S.L.
External linksJ. Mol. Biol. / PubMed:33539876
MethodsX-ray diffraction
Resolution2.31 Å
Structure data

PDB-6vo7:
Crystal structure of PI3K-alpha Ras Binding Domain (RBD)
Method: X-RAY DIFFRACTION / Resolution: 2.31 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsONCOPROTEIN / Ras binding domain / oncogenic signaling / effector

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