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-Structure paper
Title | Tislelizumab uniquely binds to the CC' loop of PD-1 with slow-dissociated rate and complete PD-L1 blockage. |
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Journal, issue, pages | Febs Open Bio, Vol. 11, Page 782-792, Year 2021 |
Publish date | Jul 2, 2020 (structure data deposition date) |
Authors | Hong, Y. / Feng, Y. / Sun, H. / Zhang, B. / Wu, H. / Zhu, Q. / Li, Y. / Zhang, T. / Zhang, Y. / Cui, X. ...Hong, Y. / Feng, Y. / Sun, H. / Zhang, B. / Wu, H. / Zhu, Q. / Li, Y. / Zhang, T. / Zhang, Y. / Cui, X. / Li, Z. / Song, X. / Li, K. / Liu, M. / Liu, Y. |
External links | Febs Open Bio / PubMed:33527708 |
Methods | X-ray diffraction |
Resolution | 3.2 Å |
Structure data | PDB-7cgw: |
Chemicals | ChemComp-NAG: |
Source |
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Keywords | ANTITUMOR PROTEIN / Tislelizumab / PD-1 / antibody |