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Structure paper

TitleHeat activates the AAA+ HslUV protease by melting an axial autoinhibitory plug.
Journal, issue, pagesCell Rep, Vol. 34, Page 108639-108639, Year 2021
Publish dateJul 26, 2019 (structure data deposition date)
AuthorsBaytshtok, V. / Fei, X. / Shih, T.T. / Grant, R.A. / Santos, J.C. / Baker, T.A. / Sauer, R.T.
External linksCell Rep / PubMed:33472065
MethodsX-ray diffraction
Resolution3.447 - 3.741 Å
Structure data

PDB-6pxi:
The crystal structure of a singly capped HslUV complex with an axial pore plug and a HslU E257Q mutation
Method: X-RAY DIFFRACTION / Resolution: 3.447 Å

PDB-6pxk:
3.65 Angstroms resolution structure of HslU with an axial-channel plug
Method: X-RAY DIFFRACTION / Resolution: 3.647 Å

PDB-6pxl:
3.74 Angstroms resolution structure of HlsU with an axial-channel plug
Method: X-RAY DIFFRACTION / Resolution: 3.741 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

Source
  • escherichia coli (E. coli)
KeywordsHYDROLASE / AAA+ ATPase / peptidase

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