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Structure paper

TitleThe Role of the HLA Class I alpha 2 Helix in Determining Ligand Hierarchy for the Killer Cell Ig-like Receptor 3DL1.
Journal, issue, pagesJ Immunol., Vol. 206, Page 849-860, Year 2021
Publish dateSep 24, 2020 (structure data deposition date)
AuthorsSaunders, P.M. / MacLachlan, B.J. / Widjaja, J. / Wong, S.C. / Oates, C.V.L. / Rossjohn, J. / Vivian, J.P. / Brooks, A.G.
External linksJ Immunol. / PubMed:33441440
MethodsX-ray diffraction
Resolution2 - 2.4 Å
Structure data

PDB-7k80:
KIR3DL1*001 in complex with HLA-A*24:02 presenting the RYPLTFGW peptide
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-7k81:
KIR3DL1*005 in complex with HLA-A*24:02 presenting the RYPLTFGW peptide
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-FMT:
FORMIC ACID

ChemComp-ACT:
ACETATE ION

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsIMMUNE SYSTEM / KIR receptor / HLA / peptide presentation

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