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TitleMutations in SKI in Shprintzen-Goldberg syndrome lead to attenuated TGF-beta responses through SKI stabilization.
Journal, issue, pagesElife, Vol. 10, Year 2021
Publish dateJul 27, 2020 (structure data deposition date)
AuthorsGori, I. / George, R. / Purkiss, A.G. / Strohbuecker, S. / Randall, R.A. / Ogrodowicz, R. / Carmignac, V. / Faivre, L. / Joshi, D. / Kjaer, S. / Hill, C.S.
External linksElife / PubMed:33416497
MethodsX-ray diffraction
Resolution2.03 Å
Structure data

PDB-6zvq:
Complex between SMAD2 MH2 domain and peptide from Ski corepressor
Method: X-RAY DIFFRACTION / Resolution: 2.03 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-TAR:
D(-)-TARTARIC ACID

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / Phosphoserine / Signal transduction / Transcription modulation

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