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TitleCrystal structure of bacterial cytotoxic necrotizing factor CNF Y reveals molecular building blocks for intoxication.
Journal, issue, pagesEmbo J., Vol. 40, Page e105202-e105202, Year 2021
Publish dateMar 30, 2020 (structure data deposition date)
AuthorsChaoprasid, P. / Lukat, P. / Muhlen, S. / Heidler, T. / Gazdag, E.M. / Dong, S. / Bi, W. / Ruter, C. / Kirchenwitz, M. / Steffen, A. ...Chaoprasid, P. / Lukat, P. / Muhlen, S. / Heidler, T. / Gazdag, E.M. / Dong, S. / Bi, W. / Ruter, C. / Kirchenwitz, M. / Steffen, A. / Jansch, L. / Stradal, T.E.B. / Dersch, P. / Blankenfeldt, W.
External linksEmbo J. / PubMed:33410511
MethodsX-ray diffraction
Resolution1.13 - 3.277 Å
Structure data

PDB-6yhk:
Crystal structure of full-length CNFy (C866S) from Yersinia pseudotuberculosis
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-6yhl:
Crystal structure of CNFy from Yersinia pseudotuberculosis - N-terminal fragment comprising residues 1-704
Method: X-RAY DIFFRACTION / Resolution: 3.277 Å

PDB-6yhm:
Crystal structure of the C-terminal domain of CNFy from Yersinia pseudotuberculosis
Method: X-RAY DIFFRACTION / Resolution: 1.13 Å

PDB-6yhn:
Crystal structure of domains 4-5 of CNFy from Yersinia pseudotuberculosis
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

ChemComp-BU3:
(R,R)-2,3-BUTANEDIOL

ChemComp-NA:
Unknown entry

Source
  • yersinia pseudotuberculosis (bacteria)
KeywordsTOXIN / CNF / cytotoxic necrotizing factor / deamidase / RhoA modification / RhoA activation / putative ADP-ribosyltransferase

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