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TitleStructure-based Development of Human Interleukin-1 beta-Specific Antibody That Simultaneously Inhibits Binding to Both IL-1RI and IL-1RAcP.
Journal, issue, pagesJ. Mol. Biol., Vol. 433, Page 166766-166766, Year 2020
Publish dateJul 6, 2020 (structure data deposition date)
AuthorsKuo, W.C. / Lee, C.C. / Chang, Y.W. / Pang, W. / Chen, H.S. / Hou, S.C. / Lo, S.Y. / Yang, A.S. / Wang, A.H.
External linksJ. Mol. Biol. / PubMed:33359099
MethodsX-ray diffraction
Resolution2.5 - 2.65 Å
Structure data

PDB-7chy:
Crystal Structure Of Human Il-1beta In Complex With Antibody Binding Fragment Of IgG26
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

PDB-7chz:
Crystal Structure Of Human Il-1beta In Complex With Antibody Binding Fragment Of IgG26A
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNOSUPPRESSANT / complex / antibody / interleukin-1beta

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