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Structure paper

TitleEnantiomer-specific activities of an LRH-1 and SF-1 dual agonist.
Journal, issue, pagesSci Rep, Vol. 10, Page 22279-22279, Year 2020
Publish dateDec 20, 2019 (structure data deposition date)
AuthorsMays, S.G. / Stec, J. / Liu, X. / D'Agostino, E.H. / Whitby, R.J. / Ortlund, E.A.
External linksSci Rep / PubMed:33335203
MethodsX-ray diffraction
Resolution1.697 Å
Structure data

PDB-6vc2:
LRH-1 bound to SS-RJW100 and a fragment of the Tif2 Coactivator
Method: X-RAY DIFFRACTION / Resolution: 1.697 Å

Chemicals

ChemComp-QU7:
(1S,3aS,6aS)-5-hexyl-4-phenyl-3a-(1-phenylethenyl)-1,2,3,3a,6,6a-hexahydropentalen-1-ol

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / Nuclear hormone receptor

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