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TitleReceptor-gated IL-2 delivery by an anti-human IL-2 antibody activates regulatory T cells in three different species.
Journal, issue, pagesSci Transl Med, Vol. 12, Year 2020
Publish dateMar 23, 2020 (structure data deposition date)
AuthorsKarakus, U. / Sahin, D. / Mittl, P.R.E. / Mooij, P. / Koopman, G. / Boyman, O.
External linksSci Transl Med / PubMed:33328333
MethodsX-ray diffraction
Resolution2.89 Å
Structure data

PDB-6ye3:
IL-2 in complex with a Fab fragment from UFKA-20
Method: X-RAY DIFFRACTION / Resolution: 2.89 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / IL-2 / Fab / Treg

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