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Structure paper

TitlePotent Henipavirus Neutralization by Antibodies Recognizing Diverse Sites on Hendra and Nipah Virus Receptor Binding Protein.
Journal, issue, pagesCell, Vol. 183, Page 1536-1550.e17, Year 2020
Publish dateFeb 25, 2020 (structure data deposition date)
AuthorsDong, J. / Cross, R.W. / Doyle, M.P. / Kose, N. / Mousa, J.J. / Annand, E.J. / Borisevich, V. / Agans, K.N. / Sutton, R. / Nargi, R. ...Dong, J. / Cross, R.W. / Doyle, M.P. / Kose, N. / Mousa, J.J. / Annand, E.J. / Borisevich, V. / Agans, K.N. / Sutton, R. / Nargi, R. / Majedi, M. / Fenton, K.A. / Reichard, W. / Bombardi, R.G. / Geisbert, T.W. / Crowe Jr., J.E.
External linksCell / PubMed:33306954
MethodsX-ray diffraction
Resolution2 - 3.4 Å
Structure data

PDB-6vy4:
Crystal structure of Hendra receptor binding protein head domain in complex with human neutralizing antibody HENV-32
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-6vy5:
Crystal structure of Nipah receptor binding protein head domain in complex with human neutralizing antibody HENV-26
Method: X-RAY DIFFRACTION / Resolution: 3.4 Å

PDB-6vy6:
Crystal structure of Hendra receptor binding protein head domain in complex with human neutralizing antibody HENV-26
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-IPA:
ISOPROPYL ALCOHOL / alkaloid*YM

ChemComp-HOH:
WATER

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-CL:
Unknown entry

ChemComp-ZN:
Unknown entry

Source
  • hendra henipavirus
  • homo sapiens (human)
  • nipah henipavirus
KeywordsVIRAL PROTEIN/IMMUNE SYSTEM / henipavirus / Hendra virus / receptor binding protein / antibody / antibody-antigen complex / VIRAL PROTEIN-IMMUNE SYSTEM complex

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