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Structure paper

TitleIncorporating a Thiophosphate Modification into a Common RNA Tetraloop Motif Causes an Unanticipated Stability Boost.
Journal, issue, pagesBiochemistry, Vol. 59, Page 4627-4637, Year 2020
Publish dateJul 25, 2020 (structure data deposition date)
AuthorsPallan, P.S. / Lybrand, T.P. / Schlegel, M.K. / Harp, J.M. / Jahns, H. / Manoharan, M. / Egli, M.
External linksBiochemistry / PubMed:33275419
MethodsX-ray diffraction
Resolution1.2 - 1.25 Å
Structure data

PDB-7jjd:
Sarcin-ricin loop with guanosine monothiophosphate residue.
Method: X-RAY DIFFRACTION / Resolution: 1.21 Å

PDB-7jje:
Sarcin-ricin loop with guanosine dithiophosphate residue.
Method: X-RAY DIFFRACTION / Resolution: 1.25 Å

PDB-7jjf:
Sarcin-ricin loop with modified residue.
Method: X-RAY DIFFRACTION / Resolution: 1.2 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

Source
  • synthetic construct (others)
  • escherichia coli (E. coli)
KeywordsRNA / Sarcin-ricin loop / RNA crystal structure / RNA tetraloops / DNA-RNA HYBRID

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