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Structure paper

TitleStructural insights into an MsmUdgX mutant capable of both crosslinking and uracil excision capability.
Journal, issue, pagesDNA Repair (Amst), Vol. 97, Page 103008-103008, Year 2021
Publish dateOct 22, 2019 (structure data deposition date)
AuthorsJia, Q. / Zeng, H. / Tu, J. / Sun, L. / Cao, W. / Xie, W.
External linksDNA Repair (Amst) / PubMed:33248387
MethodsX-ray diffraction
Resolution1.80007323734 - 2.0642595849 Å
Structure data

PDB-6l5a:
The structure of the UdgX mutant H109E at a pre-excision state
Method: X-RAY DIFFRACTION / Resolution: 1.80007323734 Å

PDB-6l5b:
The structure of the UdgX mutant H109E at a post-excision state
Method: X-RAY DIFFRACTION / Resolution: 2.00004990268 Å

PDB-6l6s:
The structure of the UdgX mutant H109E crosslinked to single-stranded DNA
Method: X-RAY DIFFRACTION / Resolution: 2.0642595849 Å

Chemicals

ChemComp-SF4:
IRON/SULFUR CLUSTER

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • mycolicibacterium smegmatis mc2 155 (bacteria)
  • synthetic construct (others)
KeywordsDNA BINDING PROTEIN / UdgX / covalent complex / protein-DNA interaction / DNA repair / glycosylase

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