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Structure paper

TitleMolecular basis for a germline-biased neutralizing antibody response to SARS-CoV-2.
Journal, issue, pagesBiorxiv, Year 2020
Publish dateOct 15, 2020 (structure data deposition date)
AuthorsClark, S.A. / Clark, L.E. / Pan, J. / Coscia, A. / McKay, L.G.A. / Shankar, S. / Johnson, R.I. / Griffiths, A. / Abraham, J.
External linksBiorxiv / PubMed:33200128
MethodsX-ray diffraction
Resolution2.102 - 2.792 Å
Structure data

PDB-7kfv:
Structural basis for a germline-biased antibody response to SARS-CoV-2 (RBD:C1A-B12 Fab)
Method: X-RAY DIFFRACTION / Resolution: 2.102 Å

PDB-7kfw:
Structural basis for a germline-biased antibody response to SARS-CoV-2 (RBD:C1A-B3 Fab)
Method: X-RAY DIFFRACTION / Resolution: 2.792 Å

PDB-7kfx:
Structural basis for a germline-biased antibody response to SARS-CoV-2 (RBD:C1A-C2 Fab)
Method: X-RAY DIFFRACTION / Resolution: 2.226 Å

PDB-7kfy:
Structural basis for a germline-biased antibody response to SARS-CoV-2 (RBD:C1A-F10 Fab)
Method: X-RAY DIFFRACTION / Resolution: 2.157 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • severe acute respiratory syndrome coronavirus 2
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM/Viral protein / COVID-19 / SARS-CoV-2 / neutralizing antibody / affinity maturation / IMMUNE SYSTEM / IMMUNE SYSTEM-Viral protein complex

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