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Structure paper

TitleCrystal structure of a guanine nucleotide exchange factor encoded by the scrub typhus pathogen Orientia tsutsugamushi .
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 117, Page 30380-30390, Year 2020
Publish dateMay 18, 2020 (structure data deposition date)
AuthorsLim, C. / Berk, J.M. / Blaise, A. / Bircher, J. / Koleske, A.J. / Hochstrasser, M. / Xiong, Y.
External linksProc. Natl. Acad. Sci. USA / PubMed:33184172
MethodsX-ray diffraction
Resolution1.6 - 2.91 Å
Structure data

PDB-6x1g:
Crystal structure of a GEF domain from the Orientia tsutsugamushi protein OtDUB in complex with Rac1
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-6x1h:
Crystal structure of a guanine nucleotide exchange factor (GEF) domain from the Orientia tsutsugamushi protein OtDUB
Method: X-RAY DIFFRACTION / Resolution: 2.91 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-NI:
NICKEL (II) ION

Source
  • orientia tsutsugamushi (bacteria)
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN/HYDROLASE / guanine nucleotide exchange factor / GEF / Rac1 / GTPase / Orientia tsutsugamushi / scrub typhus / SIGNALING PROTEIN / SIGNALING PROTEIN-HYDROLASE complex

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