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Structure paper

Titlestructural characterization of the interaction between the C-terminal domain of the influenza polymerase PA subunit and an optimized small peptide inhibitor.
Journal, issue, pagesAntiviral Res., Vol. 185, Page 104971-104971, Year 2020
Publish dateSep 30, 2019 (structure data deposition date)
AuthorsHejdanek, J. / Radilova, K. / Pachl, P. / Hodek, J. / Machara, A. / Weber, J. / Rezacova, P. / Konvalinka, J. / Kozisek, M.
External linksAntiviral Res. / PubMed:33166574
MethodsX-ray diffraction
Resolution1.6 Å
Structure data

PDB-6syi:
C-TERMINAL DOMAIN OF INFLUENZA POLYMERASE PA SUBUNIT AND OPTIMIZED SMALL PEPTIDE INHIBITOR
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-PGE:
TRIETHYLENE GLYCOL

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • influenza a virus (a/wisconsin/629-d00036/2009(h1n1))
  • synthetic construct (others)
KeywordsVIRAL PROTEIN / neuraminidase / influenza / complex

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