EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Structure of human endo-alpha-1,2-mannosidase (MANEA), an antiviral host-glycosylation target.
ジャーナル・号・ページ	Proc. Natl. Acad. Sci. USA, Vol. 117, Page 29595-29601, Year 2020
掲載日	2020年6月14日 (構造データの登録日)
著者	Sobala, L.F. / Fernandes, P.Z. / Hakki, Z. / Thompson, A.J. / Howe, J.D. / Hill, M. / Zitzmann, N. / Davies, S. / Stamataki, Z. / Butters, T.D. ...Sobala, L.F. / Fernandes, P.Z. / Hakki, Z. / Thompson, A.J. / Howe, J.D. / Hill, M. / Zitzmann, N. / Davies, S. / Stamataki, Z. / Butters, T.D. / Alonzi, D.S. / Williams, S.J. / Davies, G.J.
リンク	Proc. Natl. Acad. Sci. USA / PubMed:33154157
手法	X線回折
解像度	1.09 - 3 Å
構造データ	PDB-6zdc: Structure of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with nickel 手法: X-RAY DIFFRACTION / 解像度: 2.251 Å PDB-6zdf: Structure of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with HEPES 手法: X-RAY DIFFRACTION / 解像度: 3.0 Å PDB-6zdk: Structure of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with HEPES and hexatungstotellurate(VI) TEW 手法: X-RAY DIFFRACTION / 解像度: 2.0 Å PDB-6zdl: Structure of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with GlcIFG and hexatungstotellurate(VI) TEW 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-6zfa: Structure of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with GlcIFG, alpha-1,2-mannobiose and hexatungstotellurate(VI) TEW 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-6zfn: Structure of an inactive E404Q variant of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with 1-methyl alpha-1,2-mannobiose 手法: X-RAY DIFFRACTION / 解像度: 1.1 Å PDB-6zfq: Structure of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with bis-tris 手法: X-RAY DIFFRACTION / 解像度: 1.2 Å PDB-6zj1: Structure of an inactive E404Q variant of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with tetrasaccharide N-glycan fragment and hexatungstotellurate(VI) TEW 手法: X-RAY DIFFRACTION / 解像度: 1.957 Å PDB-6zj5: Structure of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with GlcDMJ and hexatungstotellurate(VI) TEW 手法: X-RAY DIFFRACTION / 解像度: 2.269 Å PDB-6zj6: Structure of the GH99 endo-alpha-mannanase from Bacteroides xylanisolvens in complex with cyclohexylmethyl-Glc-1,3-isofagomine 手法: X-RAY DIFFRACTION / 解像度: 1.09 Å
化合物	ChemComp-NI: NICKEL (II) ION ChemComp-HOH: WATER ChemComp-EPE: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / HEPES / pH緩衝剤YM ChemComp-MG: Unknown entry / マグネシウムジカチオン ChemComp-TEW: 6-tungstotellurate(VI) ChemComp-IFM: 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE / イソファゴミン ChemComp-GLC: alpha-D-glucopyranose / α-D-グルコピラノ-ス ChemComp-SO4: SULFATE ION / 硫酸ジアニオン ChemComp-BTB: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / ビストリス / pH緩衝剤YM ChemComp-DMJ: 1-DEOXYMANNOJIRIMYCIN / デオキシマンノジリマイシン ChemComp-EDO: 1,2-ETHANEDIOL / エチレングリコ-ル ChemComp-ACT: ACETATE ION / 酢酸イオン ChemComp-QTE: methylcyclohexane / メチルシクロヘキサン
由来	homo sapiens (ヒト) bacteroides xylanisolvens xb1a (バクテリア)
キーワード	HYDROLASE / Golgi / mannosidase / retaining