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Structure paper

TitleThe structural basis for an on-off switch controlling G beta gamma-mediated inhibition of TRPM3 channels.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 117, Page 29090-29100, Year 2020
Publish dateMay 7, 2019 (structure data deposition date)
AuthorsBehrendt, M. / Gruss, F. / Enzeroth, R. / Dembla, S. / Zhao, S. / Crassous, P.A. / Mohr, F. / Nys, M. / Louros, N. / Gallardo, R. ...Behrendt, M. / Gruss, F. / Enzeroth, R. / Dembla, S. / Zhao, S. / Crassous, P.A. / Mohr, F. / Nys, M. / Louros, N. / Gallardo, R. / Zorzini, V. / Wagner, D. / Economou, A. / Rousseau, F. / Schymkowitz, J. / Philipp, S.E. / Rohacs, T. / Ulens, C. / Oberwinkler, J.
External linksProc. Natl. Acad. Sci. USA / PubMed:33122432
MethodsX-ray diffraction
Resolution1.94 Å
Structure data

PDB-6rmv:
The crystal structure of a TRP channel peptide bound to a G protein beta gamma heterodimer
Method: X-RAY DIFFRACTION / Resolution: 1.94 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsPROTEIN BINDING / G protein / TRP Channel / Inhibitor

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