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TitleGoing Platinum to the Tune of a Remarkable Guanine Quadruplex Binder: Solution- and Solid-State Investigations.
Journal, issue, pagesAngew. Chem. Int. Ed. Engl., Vol. 60, Page 2500-2507, Year 2021
Publish dateJun 8, 2020 (structure data deposition date)
AuthorsMiron, C.E. / van Staalduinen, L. / Rangaswamy, A.M. / Chen, M. / Liang, Y. / Jia, Z. / Mergny, J.L. / Petitjean, A.
External linksAngew. Chem. Int. Ed. Engl. / PubMed:33090592
MethodsX-ray diffraction
Resolution2.7 Å
Structure data

PDB-6xcl:
Crystal Structure of human telomeric DNA G-quadruplex in complex with a novel platinum(II) complex.
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-V4A:
Platinum(II) bis[3-(pyridin-2-yl)-[1,2,4]triazolo[4,3-a]pyridine]

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-K:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsDNA / guanine quadruplex / Ligand Complex

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