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Structure paper

TitleCannabidiol interactions with voltage-gated sodium channels.
Journal, issue, pagesElife, Vol. 9, Year 2020
Publish dateMay 6, 2020 (structure data deposition date)
AuthorsSait, L.G. / Sula, A. / Ghovanloo, M.R. / Hollingworth, D. / Ruben, P.C. / Wallace, B.A.
External linksElife / PubMed:33089780
MethodsX-ray diffraction
Resolution2.2 - 2.3 Å
Structure data

PDB-6yz0:
Full length Open-form Sodium Channel NavMs F208L in complex with Cannabidiol (CBD)
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-6yz2:
Full length Open-form Sodium Channel NavMs F208L
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-2CV:
HEGA-10 / detergent*YM

ChemComp-12P:
DODECAETHYLENE GLYCOL / precipitant*YM

ChemComp-CD0:
2-[(1R,2R,5S)-5-methyl-2-(prop-1-en-2-yl)cyclohexyl]-5-pentylbenzene-1,3-diol

ChemComp-HOH:
WATER

Source
  • magnetococcus marinus mc-1 (bacteria)
  • magnetococcus marinus (strain atcc baa-1437 / jcm 17883 / mc-1) (bacteria)
KeywordsMETAL TRANSPORT / Voltage Gated Sodium Channel / Membrane protein.

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