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TitleBase pairing, structural and functional insights into N4-methylcytidine (m4C) and N4,N4-dimethylcytidine (m42C) modified RNA.
Journal, issue, pagesNucleic Acids Res., Vol. 48, Page 10087-10100, Year 2020
Publish dateMay 12, 2020 (structure data deposition date)
AuthorsMao, S. / Sekula, B. / Ruszkowski, M. / Ranganathan, S.V. / Haruehanroengra, P. / Wu, Y. / Shen, F. / Sheng, J.
External linksNucleic Acids Res. / PubMed:32941619
MethodsX-ray diffraction
Resolution1.647 - 1.928 Å
Structure data

PDB-6wy2:
Crystal structure of RNA-10mer: CCGG(N4-methyl-C)GCCGG
Method: X-RAY DIFFRACTION / Resolution: 1.928 Å

PDB-6wy3:
Crystal structure of RNA-10mer: CCGG(N4,N4-dimethyl-C)GCCGG; P212121 form
Method: X-RAY DIFFRACTION / Resolution: 1.647 Å

PDB-6z18:
Crystal structure of RNA-10mer: CCGG(N4,N4-dimethyl-C)GCCGG; R32 form
Method: X-RAY DIFFRACTION / Resolution: 1.81 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-K:
Unknown entry

ChemComp-HOH:
WATER

Source
  • synthetic construct (others)
KeywordsRNA / RNA DUPLEX / RNA DUPLEX 10MER / N4 / N4-dimethylcytidine

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