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-Structure paper
Title | Disruption of a key ligand-H-bond network drives dissociative properties in vamorolone for Duchenne muscular dystrophy treatment. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 117, Page 24285-24293, Year 2020 |
Publish date | Mar 23, 2020 (structure data deposition date) |
Authors | Liu, X. / Wang, Y. / Gutierrez, J.S. / Damsker, J.M. / Nagaraju, K. / Hoffman, E.P. / Ortlund, E.A. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:32917814 |
Methods | X-ray diffraction |
Resolution | 1.45 - 1.6 Å |
Structure data | PDB-6w9k: PDB-6w9l: PDB-6w9m: |
Chemicals | ChemComp-TUA: ChemComp-GOL: ChemComp-HOH: ChemComp-TUS: ChemComp-TUV: |
Source |
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Keywords | HORMONE / Glucocorticoid Receptor / anti-inflammation drug |