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Structure paper

TitleThe Structural Basis of IRF-3 Activation upon Phosphorylation.
Journal, issue, pagesJ Immunol., Vol. 205, Page 1886-1896, Year 2020
Publish dateJul 17, 2020 (structure data deposition date)
AuthorsJing, T. / Zhao, B. / Xu, P. / Gao, X. / Chi, L. / Han, H. / Sankaran, B. / Li, P.
External linksJ Immunol. / PubMed:32826280
MethodsX-ray diffraction
Resolution1.68 - 2.23 Å
Structure data

PDB-7jfl:
Crystal structure of human phosphorylated IRF-3 bound to CBP
Method: X-RAY DIFFRACTION / Resolution: 1.68 Å

PDB-7jfm:
Crystal structure of mouse phosphorylated IRF-3 bound to CBP
Method: X-RAY DIFFRACTION / Resolution: 2.23 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / transcription factor / phosphorylation / innate immunity

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