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TitleMolecular and structural basis for Lewis glycan recognition by a cancer-targeting antibody.
Journal, issue, pagesBiochem. J., Vol. 477, Page 3219-3235, Year 2020
Publish dateMay 26, 2020 (structure data deposition date)
AuthorsSoliman, C. / Guy, A.J. / Chua, J.X. / Vankemmelbeke, M. / McIntosh, R.S. / Eastwood, S. / Truong, V.K. / Elbourne, A. / Spendlove, I. / Durrant, L.G. / Ramsland, P.A.
External linksBiochem. J. / PubMed:32789497
MethodsX-ray diffraction
Resolution2.29 Å
Structure data

PDB-6x5e:
Crystal structure of a Lewis-binding Fab (ch88.2)
Method: X-RAY DIFFRACTION / Resolution: 2.29 Å

Chemicals

ChemComp-NI:
NICKEL (II) ION

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / immunoglobulin / chimeric antibody / antigen binding fragment / Lewis-binding antibody

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