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TitleStructural basis of CD4 downregulation by HIV-1 Nef.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 27, Page 822-828, Year 2020
Publish dateOct 23, 2019 (structure data deposition date)
AuthorsKwon, Y. / Kaake, R.M. / Echeverria, I. / Suarez, M. / Karimian Shamsabadi, M. / Stoneham, C. / Ramirez, P.W. / Kress, J. / Singh, R. / Sali, A. ...Kwon, Y. / Kaake, R.M. / Echeverria, I. / Suarez, M. / Karimian Shamsabadi, M. / Stoneham, C. / Ramirez, P.W. / Kress, J. / Singh, R. / Sali, A. / Krogan, N. / Guatelli, J. / Jia, X.
External linksNat. Struct. Mol. Biol. / PubMed:32719457
MethodsX-ray diffraction
Resolution3 Å
Structure data

PDB-6uri:
HIV-1 Nef in complex with the CD4 cytoplasmic domain and the AP2 clathrin adaptor complex
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • rattus norvegicus (Norway rat)
  • homo sapiens (human)
  • human immunodeficiency virus 1
KeywordsVIRAL PROTEIN / CD4

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