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Structure paper

TitleStructure and function of a malaria transmission blocking vaccine targeting Pfs230 and Pfs230-Pfs48/45 proteins.
Journal, issue, pagesCommun Biol, Vol. 3, Page 395-395, Year 2020
Publish dateApr 5, 2019 (structure data deposition date)
AuthorsSingh, K. / Burkhardt, M. / Nakuchima, S. / Herrera, R. / Muratova, O. / Gittis, A.G. / Kelnhofer, E. / Reiter, K. / Smelkinson, M. / Veltri, D. ...Singh, K. / Burkhardt, M. / Nakuchima, S. / Herrera, R. / Muratova, O. / Gittis, A.G. / Kelnhofer, E. / Reiter, K. / Smelkinson, M. / Veltri, D. / Swihart, B.J. / Shimp Jr., R. / Nguyen, V. / Zhang, B. / MacDonald, N.J. / Duffy, P.E. / Garboczi, D.N. / Narum, D.L.
External linksCommun Biol / PubMed:32709983
MethodsX-ray diffraction
Resolution2.385 Å
Structure data

PDB-6ohg:
Structure of Plasmodium falciparum vaccine candidate Pfs230D1M in complex with the Fab of a transmission blocking antibody
Method: X-RAY DIFFRACTION / Resolution: 2.385 Å

Chemicals

ChemComp-ACY:
ACETIC ACID

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-PDO:
1,3-PROPANDIOL

ChemComp-MOH:
METHANOL

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • plasmodium falciparum (malaria parasite P. falciparum)
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / malaria / transmission blocking / sexual stage / 6 cysteine-rich Pfs230

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