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-Structure paper
Title | Structural insights into human Arginase-1 pH dependence and its inhibition by the small molecule inhibitor CB-1158. |
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Journal, issue, pages | J Struct Biol X, Vol. 4, Page 100014-100014, Year 2020 |
Publish date | Dec 17, 2018 (structure data deposition date) |
![]() | Grobben, Y. / Uitdehaag, J.C.M. / Willemsen-Seegers, N. / Tabak, W.W.A. / de Man, J. / Buijsman, R.C. / Zaman, G.J.R. |
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Methods | X-ray diffraction |
Resolution | 1.5 - 1.66 Å |
Structure data | ![]() PDB-6q92: ![]() PDB-6q9p: ![]() PDB-6qaf: |
Chemicals | ![]() ChemComp-MN: ![]() ChemComp-ABH: ![]() ChemComp-NA: ![]() ChemComp-HOH: ![]() ChemComp-XC3: |
Source |
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![]() | HYDROLASE / hydrolase inhibitor / borate / manganese cluster / pH-dependent / arignase inhibitor |