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TitleStructure and selectivity engineering of the M1muscarinic receptor toxin complex.
Journal, issue, pagesScience, Vol. 369, Page 161-167, Year 2020
Publish dateApr 13, 2020 (structure data deposition date)
AuthorsMaeda, S. / Xu, J. / N Kadji, F.M. / Clark, M.J. / Zhao, J. / Tsutsumi, N. / Aoki, J. / Sunahara, R.K. / Inoue, A. / Garcia, K.C. / Kobilka, B.K.
External linksScience / PubMed:32646996
MethodsX-ray diffraction
Resolution2.55 Å
Structure data

PDB-6wjc:
Muscarinic acetylcholine receptor 1 - muscarinic toxin 7 complex
Method: X-RAY DIFFRACTION / Resolution: 2.55 Å

Chemicals

ChemComp-ACM:
ACETAMIDE

ChemComp-Y01:
CHOLESTEROL HEMISUCCINATE

ChemComp-OIN:
(1R,5S)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL (2R)-3-HYDROXY-2-PHENYLPROPANOATE / medication, alkaloid*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • enterobacteria phage t4 (virus)
  • dendroaspis angusticeps (eastern green mamba)
KeywordsMEMBRANE PROTEIN / GPCR / natural toxin

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