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| Title | Topoisomerase Inhibitors Addressing Fluoroquinolone Resistance in Gram-Negative Bacteria. |
|---|---|
| Journal, issue, pages | J. Med. Chem., Vol. 63, Page 7773-7816, Year 2020 |
| Publish date | Mar 24, 2020 (structure data deposition date) |
 Authors | Skepper, C.K. / Armstrong, D. / Balibar, C.J. / Bauer, D. / Bellamacina, C. / Benton, B.M. / Bussiere, D. / De Pascale, G. / De Vicente, J. / Dean, C.R. ...Skepper, C.K. / Armstrong, D. / Balibar, C.J. / Bauer, D. / Bellamacina, C. / Benton, B.M. / Bussiere, D. / De Pascale, G. / De Vicente, J. / Dean, C.R. / Dhumale, B. / Fisher, L.M. / Fuller, J. / Fulsunder, M. / Holder, L.M. / Hu, C. / Kantariya, B. / Lapointe, G. / Leeds, J.A. / Li, X. / Lu, P. / Lvov, A. / Ma, S. / Madhavan, S. / Malekar, S. / McKenney, D. / Mergo, W. / Metzger, L. / Moser, H.E. / Mutnick, D. / Noeske, J. / Osborne, C. / Patel, A. / Patel, D. / Patel, T. / Prajapati, K. / Prosen, K.R. / Reck, F. / Richie, D.L. / Rico, A. / Sanderson, M.R. / Satasia, S. / Sawyer, W.S. / Selvarajah, J. / Shah, N. / Shanghavi, K. / Shu, W. / Thompson, K.V. / Traebert, M. / Vala, A. / Vala, L. / Veselkov, D.A. / Vo, J. / Wang, M. / Widya, M. / Williams, S.L. / Xu, Y. / Yue, Q. / Zang, R. / Zhou, B. / Rivkin, A. |
 External links | J. Med. Chem. / PubMed:32634310 |
| Methods | X-ray diffraction |
| Resolution | 3.2 Å |
| Structure data |  PDB-6waa: |
| Chemicals |  ChemComp-MPD:  ChemComp-MG:  ChemComp-CL:  ChemComp-TNJ:  ChemComp-HOH: |
| Source |
|
 Keywords | ISOMERASE/DNA/ISOMERASE INHIBITOR / DNA-Topoisomerase / ISOMERASE-DNA-ISOMERASE INHIBITOR complex |
klebsiella pneumoniae 342 (bacteria)