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Structure paper

TitleAnalysis of a preQ1-I riboswitch in effector-free and bound states reveals a metabolite-programmed nucleobase-stacking spine that controls gene regulation.
Journal, issue, pagesNucleic Acids Res., Vol. 48, Page 8146-8164, Year 2020
Publish dateFeb 15, 2020 (structure data deposition date)
AuthorsSchroeder, G.M. / Dutta, D. / Cavender, C.E. / Jenkins, J.L. / Pritchett, E.M. / Baker, C.D. / Ashton, J.M. / Mathews, D.H. / Wedekind, J.E.
External linksNucleic Acids Res. / PubMed:32597951
MethodsX-ray diffraction
Resolution1.999 - 2.681 Å
Structure data

PDB-6vuh:
APO PreQ1 riboswitch aptamer grown in Mn2+
Method: X-RAY DIFFRACTION / Resolution: 1.999 Å

PDB-6vui:
Metabolite-bound PreQ1 riboswitch with Mn2+
Method: X-RAY DIFFRACTION / Resolution: 2.681 Å

Chemicals

ChemComp-MN:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-PRF:
7-DEAZA-7-AMINOMETHYL-GUANINE

Source
  • caldanaerobacter subterraneus subsp. tengcongensis (bacteria)
KeywordsRNA / PREQ1 / PREQ0 / QUEUOSINE / RIBOSOMAL BINDING SITE / APTAMER / METABOLITE / PSEUDOKNOT / H-TYPE / RIBOSWITCH

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