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TitleA Combination of Human Broadly Neutralizing Antibodies against Hepatitis B Virus HBsAg with Distinct Epitopes Suppresses Escape Mutations.
Journal, issue, pagesCell Host Microbe, Vol. 28, Page 335-349.e6, Year 2020
Publish dateJan 17, 2020 (structure data deposition date)
AuthorsWang, Q. / Michailidis, E. / Yu, Y. / Wang, Z. / Hurley, A.M. / Oren, D.A. / Mayer, C.T. / Gazumyan, A. / Liu, Z. / Zhou, Y. ...Wang, Q. / Michailidis, E. / Yu, Y. / Wang, Z. / Hurley, A.M. / Oren, D.A. / Mayer, C.T. / Gazumyan, A. / Liu, Z. / Zhou, Y. / Schoofs, T. / Yao, K.H. / Nieke, J.P. / Wu, J. / Jiang, Q. / Zou, C. / Kabbani, M. / Quirk, C. / Oliveira, T. / Chhosphel, K. / Zhang, Q. / Schneider, W.M. / Jahan, C. / Ying, T. / Horowitz, J. / Caskey, M. / Jankovic, M. / Robbiani, D.F. / Wen, Y. / de Jong, Y.P. / Rice, C.M. / Nussenzweig, M.C.
External linksCell Host Microbe / PubMed:32504577
MethodsX-ray diffraction
Resolution1.782 Å
Structure data

PDB-6vjt:
Co-crystals of broadly neutralizing antibody with the linear epitope from Hepatitis B surface antigen
Method: X-RAY DIFFRACTION / Resolution: 1.782 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • hepatitis b virus
KeywordsANTIVIRAL PROTEIN/IMMUNE SYSTEM / Hepatitis B / HepB / Fab / Ab / antibody / ANTIVIRAL PROTEIN / ANTIVIRAL PROTEIN-IMMUNE SYSTEM complex

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