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Structure paper

TitleCrystal structure of a human plasma membrane phospholipid flippase.
Journal, issue, pagesJ. Biol. Chem., Vol. 295, Page 10180-10194, Year 2020
Publish dateDec 19, 2019 (structure data deposition date)
AuthorsNakanishi, H. / Irie, K. / Segawa, K. / Hasegawa, K. / Fujiyoshi, Y. / Nagata, S. / Abe, K.
External linksJ. Biol. Chem. / PubMed:32493773
MethodsX-ray diffraction
Resolution3.9 Å
Structure data

PDB-6lkn:
Crystal structure of ATP11C-CDC50A in PtdSer-bound E2P state
Method: X-RAY DIFFRACTION / Resolution: 3.9 Å

Chemicals

ChemComp-P5S:
O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine

ChemComp-MG:
Unknown entry

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-AH2:
1-deoxy-alpha-D-mannopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsMEMBRANE PROTEIN / P-type ATPase / flippase / apoptosis / phosphatidylserine

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