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TitleMESH1 is a cytosolic NADPH phosphatase that regulates ferroptosis.
Journal, issue, pagesNat Metab, Vol. 2, Page 270-277, Year 2020
Publish dateMay 23, 2017 (structure data deposition date)
AuthorsDing, C.C. / Rose, J. / Sun, T. / Wu, J. / Chen, P.H. / Lin, C.C. / Yang, W.H. / Chen, K.Y. / Lee, H. / Xu, E. ...Ding, C.C. / Rose, J. / Sun, T. / Wu, J. / Chen, P.H. / Lin, C.C. / Yang, W.H. / Chen, K.Y. / Lee, H. / Xu, E. / Tian, S. / Akinwuntan, J. / Zhao, J. / Guan, Z. / Zhou, P. / Chi, J.T.
External linksNat Metab / PubMed:32462112
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-5vxa:
Structure of the human Mesh1-NADPH complex
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-NDP:
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-BME:
BETA-MERCAPTOETHANOL

ChemComp-NA:
Unknown entry

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / Mesh1 NADPH

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