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TitleStructural basis for the function and inhibition of dihydroorotate dehydrogenase from Schistosoma mansoni.
Journal, issue, pagesFebs J., Vol. 288, Page 930-944, Year 2021
Publish dateNov 11, 2019 (structure data deposition date)
Authorsde Mori, R.M. / Aleixo, M.A.A. / Zapata, L.C.C. / Calil, F.A. / Emery, F.S. / Nonato, M.C.
External linksFebs J. / PubMed:32428996
MethodsX-ray diffraction
Resolution2.796 Å
Structure data

PDB-6uy4:
Crystal structure of dihydroorotate dehydrogenase from Schistosoma mansoni
Method: X-RAY DIFFRACTION / Resolution: 2.796 Å

Chemicals

ChemComp-QLA:
2-[(4-fluorophenyl)amino]-3-hydroxynaphthalene-1,4-dione

ChemComp-GOL:
GLYCEROL

ChemComp-FMN:
FLAVIN MONONUCLEOTIDE

ChemComp-HOH:
WATER

Source
  • schistosoma mansoni (invertebrata)
KeywordsOXIDOREDUCTASE/INHIBITOR / SmDHODH / class 2 dihydroorotate dehydrogenase / Schistosoma mansoni / FLAVOPROTEIN / OXIDOREDUCTASE-INHIBITOR complex

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