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Structure paper

TitleStructural and Functional Characterization of Phosphatidylinositol-Phosphate Biosynthesis in Mycobacteria.
Journal, issue, pagesJ. Mol. Biol., Vol. 432, Page 5137-5151, Year 2020
Publish dateApr 20, 2020 (structure data deposition date)
AuthorsBelcher Dufrisne, M. / Jorge, C.D. / Timoteo, C.G. / Petrou, V.I. / Ashraf, K.U. / Banerjee, S. / Clarke, O.B. / Santos, H. / Mancia, F.
External linksJ. Mol. Biol. / PubMed:32389689
MethodsX-ray diffraction
Resolution1.961 - 2.142 Å
Structure data

PDB-6wm5:
Structure of a phosphatidylinositol-phosphate synthase (PIPS) from Mycobacterium kansasii
Method: X-RAY DIFFRACTION / Resolution: 1.961 Å

PDB-6wmv:
Structure of a phosphatidylinositol-phosphate synthase (PIPS) from Mycobacterium kansasii with evidence of substrate binding
Method: X-RAY DIFFRACTION / Resolution: 2.142 Å

Chemicals

ChemComp-FLC:
CITRATE ANION

ChemComp-NA:
Unknown entry

ChemComp-PO4:
PHOSPHATE ION

ChemComp-TCE:
3,3',3''-phosphanetriyltripropanoic acid

ChemComp-OLC:
(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate

ChemComp-8K6:
Octadecane

ChemComp-GOL:
GLYCEROL

ChemComp-XP4:
1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE / DMPA, phospholipid*YM

ChemComp-HOH:
WATER

ChemComp-LIP:
L-MYO-INOSITOL-1-PHOSPHATE

ChemComp-1PE:
PENTAETHYLENE GLYCOL / precipitant*YM

ChemComp-C5P:
CYTIDINE-5'-MONOPHOSPHATE

Source
  • archaeoglobus fulgidus (archaea)
  • mycobacterium kansasii (bacteria)
  • mycobacterium kansasii atcc 12478 (bacteria)
KeywordsMEMBRANE PROTEIN / CDP-alcohol phosphotransferase / Structural Genomics / PSI-Biology / New York Consortium on Membrane Protein Structure / NYCOMPS

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