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Structure paper

TitleMolecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder.
Journal, issue, pagesNeuron, Vol. 107, Page 52-64.e7, Year 2020
Publish dateAug 9, 2019 (structure data deposition date)
AuthorsBradberry, M.M. / Courtney, N.A. / Dominguez, M.J. / Lofquist, S.M. / Knox, A.T. / Sutton, R.B. / Chapman, E.R.
External linksNeuron / PubMed:32362337
MethodsX-ray diffraction
Resolution1.17 - 1.7 Å
Structure data

PDB-6tz3:
Crystal Structure of Human Synaptotagmin 1 C2B without Ca2+
Method: X-RAY DIFFRACTION / Resolution: 1.17 Å

PDB-6u41:
1.7 angstrom structure of a pathogenic human Syt 1 C2B (D304G)
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-6u4u:
1.3 A structure of a pathogenic human Syt 1 C2B (I368T)
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

PDB-6u4w:
1.4 A structure of a pathogenic human Syt 1 C2B (D366E)
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsEXOCYTOSIS / C2 domain / C2B / Greek Key / Baker-Gordon syndrome

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