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TitleA CLC-ec1 mutant reveals global conformational change and suggests a unifying mechanism for the CLC Cl - /H + transport cycle.
Journal, issue, pagesElife, Vol. 9, Year 2020
Publish dateNov 24, 2019 (structure data deposition date)
AuthorsChavan, T.S. / Cheng, R.C. / Jiang, T. / Mathews, I.I. / Stein, R.A. / Koehl, A. / Mchaourab, H.S. / Tajkhorshid, E. / Maduke, M.
External linksElife / PubMed:32310757
MethodsX-ray diffraction
Resolution2.62 Å
Structure data

PDB-6v2j:
Crystal structure of ClC-ec1 triple mutant (E113Q, E148Q, E203Q)
Method: X-RAY DIFFRACTION / Resolution: 2.62 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • escherichia coli (strain k12) (bacteria)
KeywordsTRANSPORT PROTEIN / chloride transporters / CLC-ec1

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