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Structure paper

TitleStructural and kinetic evidence of aging after organophosphate inhibition of human Cathepsin A.
Journal, issue, pagesBiochem. Pharmacol., Vol. 177, Page 113980-113980, Year 2020
Publish dateApr 9, 2020 (structure data deposition date)
AuthorsBouknight, K.D. / Jurkouich, K.M. / Compton, J.R. / Khavrutskii, I.V. / Guelta, M.A. / Harvey, S.P. / Legler, P.M.
External linksBiochem. Pharmacol. / PubMed:32305437
MethodsX-ray diffraction
Resolution2.21 Å
Structure data

PDB-6wia:
CRYSTAL STRUCTURE OF HUMAN PROTECTIVE PROTEIN/CATHEPSIN A, DFP-INHIBITED (AGED)
Method: X-RAY DIFFRACTION / Resolution: 2.21 Å

Chemicals

ChemComp-ACT:
ACETATE ION

ChemComp-CD:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / Lysosomal / Cathepsin A / CatA / CTSA / organophosphate / renin-angiotensin system (RAS)

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