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-Structure paper
Title | Nek7 conformational flexibility and inhibitor binding probed through protein engineering of the R-spine. |
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Journal, issue, pages | Biochem. J., Vol. 477, Page 1525-1539, Year 2020 |
Publish date | Jul 4, 2019 (structure data deposition date) |
Authors | Byrne, M.J. / Nasir, N. / Basmadjian, C. / Bhatia, C. / Cunnison, R.F. / Carr, K.H. / Mas-Droux, C. / Yeoh, S. / Cano, C. / Bayliss, R. |
External links | Biochem. J. / PubMed:32242624 |
Methods | X-ray diffraction |
Resolution | 2 - 3.5 Å |
Structure data | PDB-6s73: PDB-6s75: PDB-6s76: PDB-6sk9: |
Chemicals | ChemComp-F9N: ChemComp-PEG: ChemComp-GOL: ChemComp-HOH: |
Source |
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Keywords | CELL CYCLE / Kinase / mutant / inhibitor / TRANSFERASE / Ser/Thr protein kinase |