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Structure paper

TitleALegionellaeffector kinase is activated by host inositol hexakisphosphate.
Journal, issue, pagesJ. Biol. Chem., Vol. 295, Page 6214-6224, Year 2020
Publish dateFeb 17, 2020 (structure data deposition date)
AuthorsSreelatha, A. / Nolan, C. / Park, B.C. / Pawlowski, K. / Tomchick, D.R. / Tagliabracci, V.S.
External linksJ. Biol. Chem. / PubMed:32229585
MethodsX-ray diffraction
Resolution1.85 - 2.65 Å
Structure data

PDB-6vvc:
Legionella pneumophila Lpg2603 kinase
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-6vvd:
Legionella pneumophila Lpg2603 kinase bound to IP6
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

PDB-6vve:
Legionella pneumophila Lpg2603 kinase bound to IP6, Mn2+, and ADP
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

ChemComp-IHP:
INOSITOL HEXAKISPHOSPHATE

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-MN:
Unknown entry

Source
  • legionella pneumophila (bacteria)
KeywordsTRANSFERASE / phosphorylation / kinase / IP6 / ADP

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