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Structure paper

TitleStructural insight into the recognition of pathogen-derived phosphoglycolipids by C-type lectin receptor DCAR.
Journal, issue, pagesJ. Biol. Chem., Vol. 295, Page 5807-5817, Year 2020
Publish dateSep 25, 2019 (structure data deposition date)
AuthorsOmahdi, Z. / Horikawa, Y. / Nagae, M. / Toyonaga, K. / Imamura, A. / Takato, K. / Teramoto, T. / Ishida, H. / Kakuta, Y. / Yamasaki, S.
External linksJ. Biol. Chem. / PubMed:32139512
MethodsX-ray diffraction
Resolution1.84 - 2.304 Å
Structure data

PDB-6kzr:
Crystal structure of mouse DCAR2 CRD domain
Method: X-RAY DIFFRACTION / Resolution: 2.304 Å

PDB-6lfj:
Crystal structure of mouse DCAR2 CRD domain complex with IPM2
Method: X-RAY DIFFRACTION / Resolution: 1.84 Å

PDB-6lkr:
Crystal structure of mouse DCAR2 CRD domain complex
Method: X-RAY DIFFRACTION / Resolution: 1.84 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-B3P:
2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-MAN:
alpha-D-mannopyranose

ChemComp-IPD:
D-MYO-INOSITOL-1-PHOSPHATE

Source
  • mus musculus (house mouse)
KeywordsSUGAR BINDING PROTEIN / C-type lectin

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