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TitleCrystal structure of Haemophilus influenzae 3-isopropylmalate dehydrogenase (LeuB) in complex with the inhibitor O-isobutenyl oxalylhydroxamate.
Journal, issue, pagesBiochem. Biophys. Res. Commun., Vol. 524, Page 996-1002, Year 2020
Publish dateJan 28, 2020 (structure data deposition date)
AuthorsMiggiano, R. / Martignon, S. / Minassi, A. / Rossi, F. / Rizzi, M.
External linksBiochem. Biophys. Res. Commun. / PubMed:32059844
MethodsX-ray diffraction
Resolution2.09 Å
Structure data

PDB-6xxy:
Crystal structure of Haemophilus influenzae 3-isopropylmalate dehydrogenase in complex with O-isobutenyl oxalylhydroxamate.
Method: X-RAY DIFFRACTION / Resolution: 2.09 Å

Chemicals

ChemComp-NAD:
NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM

ChemComp-MG:
Unknown entry

ChemComp-O45:
2-(2-methylprop-2-enoxyamino)-2-oxidanylidene-ethanoic acid

ChemComp-HOH:
WATER

Source
  • haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd) (bacteria)
KeywordsOXIDOREDUCTASE / Haemophilus influenzae / leucine biosynthetis / 3-isopropylmalate dehydrogenase / inhibitor

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