+Search query
-Structure paper
Title | Selective and Potent CDK8/19 Inhibitors Enhance NK-Cell Activity and Promote Tumor Surveillance. |
---|---|
Journal, issue, pages | Mol. Cancer Ther., Vol. 19, Page 1018-1030, Year 2020 |
Publish date | Feb 25, 2019 (structure data deposition date) |
Authors | Hofmann, M.H. / Mani, R. / Engelhardt, H. / Impagnatiello, M.A. / Carotta, S. / Kerenyi, M. / Lorenzo-Herrero, S. / Bottcher, J. / Scharn, D. / Arnhof, H. ...Hofmann, M.H. / Mani, R. / Engelhardt, H. / Impagnatiello, M.A. / Carotta, S. / Kerenyi, M. / Lorenzo-Herrero, S. / Bottcher, J. / Scharn, D. / Arnhof, H. / Zoephel, A. / Schnitzer, R. / Gerstberger, T. / Sanderson, M.P. / Rajgolikar, G. / Goswami, S. / Vasu, S. / Ettmayer, P. / Gonzalez, S. / Pearson, M. / McConnell, D.B. / Kraut, N. / Muthusamy, N. / Moll, J. |
External links | Mol. Cancer Ther. / PubMed:32024684 |
Methods | X-ray diffraction |
Resolution | 2.19 - 2.7 Å |
Structure data | PDB-6qtg: PDB-6qtj: PDB-6r3s: |
Chemicals | ChemComp-JH8: ChemComp-HOH: ChemComp-JHK: ChemComp-JRE: ChemComp-EDO: ChemComp-FMT: |
Source |
|
Keywords | CELL CYCLE / Inhibitor / Complex / KINASE |