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TitleIn vivocrystals reveal critical features of the interaction between cystic fibrosis transmembrane conductance regulator (CFTR) and the PDZ2 domain of Na+/H+exchange cofactor NHERF1.
Journal, issue, pagesJ. Biol. Chem., Vol. 295, Page 4464-4476, Year 2020
Publish dateMay 16, 2019 (structure data deposition date)
AuthorsMartin, E.R. / Barbieri, A. / Ford, R.C. / Robinson, R.C.
External linksJ. Biol. Chem. / PubMed:32014995
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-6rqr:
Extended NHERF1 PDZ2 domain in complex with the PDZ-binding motif of CFTR
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / Complex / PDZ / PDZ-binding motif

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