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TitleUnstructured regions in IRE1 alpha specify BiP-mediated destabilisation of the luminal domain dimer and repression of the UPR.
Journal, issue, pagesElife, Vol. 8, Year 2019
Publish dateAug 6, 2019 (structure data deposition date)
AuthorsAmin-Wetzel, N. / Neidhardt, L. / Yan, Y. / Mayer, M.P. / Ron, D.
External linksElife / PubMed:31873072
MethodsX-ray diffraction
Resolution3.55 Å
Structure data

PDB-6shc:
Crystal structure of human IRE1 luminal domain Q105C
Method: X-RAY DIFFRACTION / Resolution: 3.55 Å

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / IRE1 / unfolded protein response / ER stress / protein quality control

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